Drug Class | Brand Name | Generic Name | Target Anxiety Disorder | How It’s Thought to Work | Benefits | Draw- backs |
Anti- convulsants | Neurontin | Gabapentin | Social Anxiety Disorder (SAD) | Affects GABA. | Usually effective within 2-4 weeks. | Sedation |
Azaspirones | BuSpar | Buspirone | Generalized Anxiety Disorder (GAD) | Enhances the activity of serotonin | Effective for many people; less sedatingthan benzo diazepines | Works slowly. |
Benzo- diazepines | Ativan Centrax Dalmane Klonopin Halcion Librium Paxipam Restoril Serax Tranxene Valium Xanax | Lorazepam Prazepam Flurazepam Clonazepam Triazolam Chlor- diazepoxide HalazepamBenzo-
diazepines Temazepam Oxazepam Clorazepate Diazepam Alprazolam | GAD, SAD, Panic Disorder | Enhances the function of GABA. | Fast-acting, some people feel better the first day. | Potentially habit-forming; can cause drowsiness; canproduce withdrawal symptoms; dis-
continuation should be done slowly. |
Beta Blockers | Inderal Tenormin | Propanolol Atenolol | SAD | Reduces ability to produce adrenaline | Fast acting; not habit-forming. | Should not be used with certain pre-existingmedical conditions, such as : asthma, congestive heart failure, diabetes,vascular disease, hyper- thyroidism and angina pectoris. |
Monoamine OxidaseInhibitors (MAOIs) | Eldepryl Marplan Nardil Parnate | Selegilene Isocarboxid Phenelzine Tranyl- cypromine | Panic Disorder, SAD, PTSD | Blocks the effect of an important brain enzyme, preventingthe breakdown of serotonin and noradrenaline. | Effective for many people, especially for patients notresponding to other medications; 2-6 weeks until improvement ocurrs. | Strict dietary restrictions and potential druginteractions; changes in blood pressure, moderate weight gain; reduced sexualresponse; insomnia. |
SelectiveSerotonin Reuptake Inhibitors (SSRIs) | Celexa Luvox Paxil Prozac Zoloft | Citalopram Fluvoxamine Paroxetine Fluoxetine Sertraline | Panic Disorder, OCD, SAD, GAD | Affects the concentration of the neuro- transmitterserotonin, a chemical in the brain thought to be linked to anxiety disorders. | Effective, with fewer side effects than other medications.4-6 weeks until improvement ocurrs. | Some people experience nausea, nervousness and diminishedsex drive. |
TricyclicAnti- depressants (TCAs) | Adapin Anafranil Aventyl Elavil Janimine Ludiomil Norpramin Pamelor Pertofrane Sinequan Surmontil Tofranil Vivactil | Doxepin Clomiprimine Nortriptyline Amitriptyline Imipramine Maprotiline Desipramine Nortriptyline Desipramine Doxepin Trimipramine Imipramine Protriptyline | Panic Disorder, PTSD, OCD (Anafranil only) | Regulates serotonin and/or noradrenaline in the brain. | Effective for many people, may take 2-6 weeks untilimprovement ocurrs. | Dry mouth; constipation; blurry vision; difficultyurinating; dizziness; low blood pressure; moderate weight gain; sexual sideeffects. |
Other Anti- depressants | Desyrel Effexor Serzone | Trazodone Venlafaxine Nefaxadone | Panic Disorder, OCD, SAD, GAD | Affects the concentration of the neuro- transmitterserotonin, a chemical in the brain thought to be linked to anxiety disorders. | Effective, with fewer side effects than other medications.4-6 weeks until improvement ocurrs. | Some people experience nausea, nervousness and diminishedsex drive. |